![Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity]()
Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding AffinityFriesen, Richard W.; Ducharme, Yves; Ball, Richard G.; Blouin, Marc; Boulet, Louise; Côté, Bernard; Frenette, Richard; Girard, Mario; Guay, Daniel; Huang, Zheng; Jones, Thomas R.; Laliberté, France; Lynch, Joseph J.; Mancini, Joseph; Martins, Evelyn; Masson, Paul; Muise, Eric; Pon, Douglas J.; Siegl, Peter K. S.; Styhler, Angela; Tsou, Nancy N.; Turner, Mervyn J.; Young, Robert N.; Girard, Yves · Journal of Medicinal Chemistry · 2003