4<i>H</i>-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4<i>H</i>-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (<i>R</i>/<i>S</i>)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors: Design, Synthesis, Pharmacology, and Structure−Activity Relationships

4H-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4H-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (R/S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors: Design, Synthesis, Pharmacology, and Structure−Activity Relationships

Pirotte, Bernard; Podona, Tchao; Diouf, Ousmane; de Tullio, Pascal; Lebrun, Philippe; Dupont, Léon; Somers, Fabian; Delarge, Jacques; Morain, Philippe; Lestage, Pierre

作者Pirotte, Bernard; Podona, Tchao; Diouf, Ousmane; de Tullio, Pascal; Lebrun, Philippe; Dupont, Léon; Somers, Fabian; Delarge, Jacques; Morain, Philippe; Lestage, Pierre
卷第41卷
期第16期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小436.48KB
发表时间1998
DOI10.1021/jm970694v
页码2946-2959

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