A Potent, Long-Acting, Orally Active (2
<i>R</i>
)-2-[(1
<i>R</i>
)-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: A Novel Muscarinic M
<sub/>3</sub>
Receptor Antagonist with High Selectivity for M
<sub/>3</sub>
over M
<sub/>2</sub>
Receptors

A Potent, Long-Acting, Orally Active (2 R )-2-[(1 R )-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: A Novel Muscarinic M ₃ Receptor Antagonist with High Selectivity for M ₃ over M ₂ Receptors

Mitsuya, Morihiro; Kobayashi, Kensuke; Kawakami, Kumiko; Satoh, Atsushi; Ogino, Yoshio; Kakikawa, Taro; Ohtake, Norikazu; Kimura, Toshifumi; Hirose, Hiroyasu; Sato, Akio; Numazawa, Tomosige; Hasegawa, Takuro; Noguchi, Kazuhito; Mase, Toshiaki

期刊名称Journal of Medicinal Chemistry
作者Mitsuya, Morihiro; Kobayashi, Kensuke; Kawakami, Kumiko; Satoh, Atsushi; Ogino, Yoshio; Kakikawa, Taro; Ohtake, Norikazu; Kimura, Toshifumi; Hirose, Hiroyasu; Sato, Akio; Numazawa, Tomosige; Hasegawa, Takuro; Noguchi, Kazuhito; Mase, Toshiaki
卷第43卷
期第26期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小150.33KB
发表时间2000-12
DOI10.1021/jm0003135
页码5017-5029

发现好书期刊，享受阅读乐趣

A Potent, Long-Acting, Orally Active (2 R )-2-[(1 R )-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: A Novel Muscarinic M 3 Receptor Antagonist with High Selectivity for M 3 over M 2 Receptors

A Potent, Long-Acting, Orally Active (2 R )-2-[(1 R )-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: A Novel Muscarinic M ₃ Receptor Antagonist with High Selectivity for M ₃ over M ₂ Receptors