Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure

Canan Koch, Stacie S.; Thoresen, Lars H.; Tikhe, Jayashree G.; Maegley, Karen A.; Almassy, Robert J.; Li, Jianke; Yu, Xiao-Hong; Zook, Scott E.; Kumpf, Robert A.; Zhang, Cathy; Boritzki, Theodore J.; Mansour, Rena N.; Zhang, Kanyin E.; Ekker, Anne; Calabrese, Chris R.; Curtin, Nicola J.; Kyle, Suzanne; Thomas, Huw D.; Wang, Lan-Zhen; Calvert, A. Hilary; Golding, Bernard T.; Griffin, Roger J.; Newell, David R.; Webber, Stephen E.; Hostomsky, Zdenek

期刊名称Journal of Medicinal Chemistry
作者Canan Koch, Stacie S.; Thoresen, Lars H.; Tikhe, Jayashree G.; Maegley, Karen A.; Almassy, Robert J.; Li, Jianke; Yu, Xiao-Hong; Zook, Scott E.; Kumpf, Robert A.; Zhang, Cathy; Boritzki, Theodore J.; Mansour, Rena N.; Zhang, Kanyin E.; Ekker, Anne; Calabrese, Chris R.; Curtin, Nicola J.; Kyle, Suzanne; Thomas, Huw D.; Wang, Lan-Zhen; Calvert, A. Hilary; Golding, Bernard T.; Griffin, Roger J.; Newell, David R.; Webber, Stephen E.; Hostomsky, Zdenek
卷第45卷
期第23期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小498.69KB
发表时间2002-11
DOI10.1021/jm020259n
页码4961-4974

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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure