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Single Mutation in the Flavivirus Envelope Protein Hinge Region Increases Neurovirulence for Mice and Monkeys but Decreases Viscerotropism for Monkeys: Relevance to Development and Safety Testing of Live, Attenuated Vaccines

Single Mutation in the Flavivirus Envelope Protein Hinge Region Increases Neurovirulence for Mice and Monkeys but Decreases Viscerotropism for Monkeys: Relevance to Development and Safety Testing of Live, Attenuated Vaccines

Monath, T. P.; Arroyo, J.; Levenbook, I.; Zhang, Z.-X.; Catalan, J.; Draper, K.; Guirakhoo, F.
  • 期刊名称Journal of Virology
  • 作者Monath, T. P.; Arroyo, J.; Levenbook, I.; Zhang, Z.-X.; Catalan, J.; Draper, K.; Guirakhoo, F.
  • 卷第76卷
  • 期第4期
  • 印刷ISSN0022-538X
  • 文件大小466.55KB
  • 发表时间2002-02-15
  • DOI10.1128/JVI.76.4.1932-1943.2002
  • 页码1932-1943
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