713 POSTER Molecularly targeted immunochemotherapeutic formulation (SEVINA) composed of pegylated trispecific disulfide linked Fv (sdFv) targeting epitopes of EGFR, PTHrP and RANKL conjugated covalently with SATA to vinorelbine eradicated osteolytic metastases of multiple myeloma inhibiting proliferation of tumor associated and bone microvascular endothelial cells inducing ADCC, AMP and type I, II, III PCD
J. Giannios; E. Michailakis; N. Alexandropulos
- 作者J. Giannios; E. Michailakis; N. Alexandropulos
- 卷第5卷
- 期第4期
- 文件大小61.46KB
- 发表时间2007
- DOI10.1016/s1359-6349(07)70512-8