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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Mark E. Schnute; Patrick M. O’Brien; Joe Nahra; Mark Morris; W. Howard Roark; Cathleen E. Hanau; Peter G. Ruminski; Jeffrey A. Scholten; Theresa R. Fletcher; Bruce C. Hamper; Jeffery N. Carroll; William C. Patt; Huey S. Shieh; Brandon Collins; Alexander G. Pavlovsky; Katherine E. Palmquist; Karl W. Aston; Jeffrey Hitchcock; Michael D. Rogers; Joseph McDonald; Adam R. Johnson; Grace E. Munie; Arthur J. Wittwer; Chiu-Fai Man; Steven L. Settle; Olga Nemirovskiy; Lillian E. Vickery; Arun Agawal; Richard D. Dyer; Teresa Sunyer
  • 作者Mark E. Schnute; Patrick M. O’Brien; Joe Nahra; Mark Morris; W. Howard Roark; Cathleen E. Hanau; Peter G. Ruminski; Jeffrey A. Scholten; Theresa R. Fletcher; Bruce C. Hamper; Jeffery N. Carroll; William C. Patt; Huey S. Shieh; Brandon Collins; Alexander G. Pavlovsky; Katherine E. Palmquist; Karl W. Aston; Jeffrey Hitchcock; Michael D. Rogers; Joseph McDonald; Adam R. Johnson; Grace E. Munie; Arthur J. Wittwer; Chiu-Fai Man; Steven L. Settle; Olga Nemirovskiy; Lillian E. Vickery; Arun Agawal; Richard D. Dyer; Teresa Sunyer
  • 卷第20卷
  • 期第2期
  • 印刷ISSN0960-894X
  • 文件大小468.39KB
  • 发表时间2010
  • DOI10.1016/j.bmcl.2009.11.081
  • 页码576-580
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