Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators

• 期刊名称Journal of Medicinal Chemistry
• 作者Ward, Simon E.; Harries, Mark; Aldegheri, Laura; Austin, Nigel E.; Ballantine, Stuart; Ballini, Elisa; Bradley, Daniel M.; Bax, Benjamin D.; Clarke, Brian P.; Harris, Andrew J.; Harrison, Stephen A.; Melarange, Rosemary A.; Mookherjee, Claudette; Mosley, Julie; Dal Negro, Gianni; Oliosi, Beatrice; Smith, Kathrine J.; Thewlis, Kevin M.; Woollard, Patrick M.; Yusaf, Shahnaz P.
• 卷第54卷
• 期第1期
• 印刷ISSN0022-2623
• 电子ISSN1520-4804
• 文件大小1334.67KB
• 发表时间2011-01-13
• DOI10.1021/jm100679e
• 页码78-94