Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence

Mark D. Andrews; Paul V. Fish; Julian Blagg; Tiffini K. Brabham; Paul E. Brennan; Alison Bridgeland; Alan D. Brown; Peter J. Bungay; Kelly M. Conlon; Nicholas J. Edmunds; Kerry af Forselles; Colleen P. Gibbons; Martin P. Green; Giles Hanton; Mark Holbrook; Alan S. Jessiman; Karin McIntosh; Gordon McMurray; Carly L. Nichols; James A. Root; R. Ian Storer; Michael R. Sutton; Robin V. Ward; Dominique Westbrook; Gavin A. Whitlock

作者Mark D. Andrews; Paul V. Fish; Julian Blagg; Tiffini K. Brabham; Paul E. Brennan; Alison Bridgeland; Alan D. Brown; Peter J. Bungay; Kelly M. Conlon; Nicholas J. Edmunds; Kerry af Forselles; Colleen P. Gibbons; Martin P. Green; Giles Hanton; Mark Holbrook; Alan S. Jessiman; Karin McIntosh; Gordon McMurray; Carly L. Nichols; James A. Root; R. Ian Storer; Michael R. Sutton; Robin V. Ward; Dominique Westbrook; Gavin A. Whitlock
卷第21卷
期第9期
印刷ISSN0960-894X
文件大小638.34KB
发表时间2011
DOI10.1016/j.bmcl.2010.11.120
页码2715-2720

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Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence