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Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties

Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties

Dr. Paul J. Coleman; John D. Schreier; Dr. Christopher D. Cox; Michael J. Breslin; David B. Whitman; Dr. Michael J. Bogusky; Dr. Georgia B. McGaughey; Dr. Rodney A. Bednar; Wei Lemaire; Dr. Scott M. Doran; Steven V. Fox; Susan L. Garson; Dr. Anthony L. Gotter; C. Meacham Harrell; Duane R. Reiss; Dr. Tamara D. Cabalu; Dr. Donghui Cui; Dr. Thomayant Prueksaritanont; Joanne Stevens; Dr. Pamela L. Tannenbaum; Dr. Richard G. Ball; Joyce Stellabott; Dr. Steven D. Young; Dr. George D. Hartman; Dr. Christopher J. Winrow; Dr. John J. Renger
  • 作者Dr. Paul J. Coleman; John D. Schreier; Dr. Christopher D. Cox; Michael J. Breslin; David B. Whitman; Dr. Michael J. Bogusky; Dr. Georgia B. McGaughey; Dr. Rodney A. Bednar; Wei Lemaire; Dr. Scott M. Doran; Steven V. Fox; Susan L. Garson; Dr. Anthony L. Gotter; C. Meacham Harrell; Duane R. Reiss; Dr. Tamara D. Cabalu; Dr. Donghui Cui; Dr. Thomayant Prueksaritanont; Joanne Stevens; Dr. Pamela L. Tannenbaum; Dr. Richard G. Ball; Joyce Stellabott; Dr. Steven D. Young; Dr. George D. Hartman; Dr. Christopher J. Winrow; Dr. John J. Renger
  • 卷第7卷
  • 期第3期
  • 印刷ISSN1860-7179
  • 电子ISSN1860-7187
  • 文件大小445.38KB
  • 发表时间2012
  • DOI10.1002/cmdc.201200025
  • 页码415-424
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