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An efficient synthesis of 3-OBn-6β,14-epoxy-bridged opiates from naltrexone and identification of a related dual MOR inverse agonist/KOR agonist

An efficient synthesis of 3-OBn-6β,14-epoxy-bridged opiates from naltrexone and identification of a related dual MOR inverse agonist/KOR agonist

Martin, David J.; FitzMorris, Paul E.; Li, Bo; Ayestas, Mario; Sally, Ellicott J.; Dersch, Christina M.; Rothman, Richard B.; Deveau, Amy M.
  • 期刊名称Bioorganic & Medicinal Chemistry Letters
  • 作者Martin, David J.; FitzMorris, Paul E.; Li, Bo; Ayestas, Mario; Sally, Ellicott J.; Dersch, Christina M.; Rothman, Richard B.; Deveau, Amy M.
  • 卷第22卷
  • 期第22期
  • 印刷ISSN0960-894X
  • 文件大小354.26KB
  • 发表时间2012-11
  • DOI10.1016/j.bmcl.2012.06.056
  • 页码6801-6805
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