Discovery of (
<i>R</i>
)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

Discovery of ( R )-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

Van Zandt, Michael C.; Whitehouse, Darren L.; Golebiowski, Adam; Ji, Min Koo; Zhang, Mingbao; Beckett, R. Paul; Jagdmann, G. Erik; Ryder, Todd R.; Sheeler, Ryan; Andreoli, Monica; Conway, Bruce; Mahboubi, Keyvan; D’Angelo, Gerard; Mitschler, Andre; Cousido-Siah, Alexandra; Ruiz, Francesc X.; Howard, Eduardo I.; Podjarny, Alberto D.; Schroeter, Hagen

期刊名称Journal of Medicinal Chemistry
作者Van Zandt, Michael C.; Whitehouse, Darren L.; Golebiowski, Adam; Ji, Min Koo; Zhang, Mingbao; Beckett, R. Paul; Jagdmann, G. Erik; Ryder, Todd R.; Sheeler, Ryan; Andreoli, Monica; Conway, Bruce; Mahboubi, Keyvan; D’Angelo, Gerard; Mitschler, Andre; Cousido-Siah, Alexandra; Ruiz, Francesc X.; Howard, Eduardo I.; Podjarny, Alberto D.; Schroeter, Hagen
卷第56卷
期第6期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小4793.24KB
发表时间2013-03-28
DOI10.1021/jm400014c
页码2568-2580

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Discovery of ( R )-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury