Identification of Tetrahydropyrido[4,3-
<i>d</i>
]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists

Identification of Tetrahydropyrido[4,3- d ]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists

Piotrowski, David W.; Futatsugi, Kentaro; Warmus, Joseph S.; Orr, Suvi T. M.; Freeman-Cook, Kevin D.; Londregan, Allyn T.; Wei, Liuqing; Jennings, Sandra M.; Herr, Michael; Coffey, Steven B.; Jiao, Wenhua; Storer, Gregory; Hepworth, David; Wang, Jian; Lavergne, Sophie Y.; Chin, Janice E.; Hadcock, John R.; Brenner, Martin B.; Wolford, Angela C.; Janssen, Ann M.; Roush, Nicole S.; Buxton, Joanne; Hinchey, Terri; Kalgutkar, Amit S.; Sharma, Raman; Flynn, Declan A.

期刊名称ACS Medicinal Chemistry Letters
作者Piotrowski, David W.; Futatsugi, Kentaro; Warmus, Joseph S.; Orr, Suvi T. M.; Freeman-Cook, Kevin D.; Londregan, Allyn T.; Wei, Liuqing; Jennings, Sandra M.; Herr, Michael; Coffey, Steven B.; Jiao, Wenhua; Storer, Gregory; Hepworth, David; Wang, Jian; Lavergne, Sophie Y.; Chin, Janice E.; Hadcock, John R.; Brenner, Martin B.; Wolford, Angela C.; Janssen, Ann M.; Roush, Nicole S.; Buxton, Joanne; Hinchey, Terri; Kalgutkar, Amit S.; Sharma, Raman; Flynn, Declan A.
卷第4卷
期第1期
印刷ISSN1948-5875
电子ISSN1948-5875
文件大小370.47KB
发表时间2013-01-10
DOI10.1021/ml300277t
页码63-68

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Identification of Tetrahydropyrido[4,3- d ]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists