β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade
- 期刊名称Organic & Biomolecular Chemistry
- 作者Ito, Ryousuke; Masukawa, Yukari; Nakada, Chika; Amari, Kanako; Nakano, Chiaki; Hoshino, Tsutomu
- 卷第12卷
- 期第23期
- 印刷ISSN1477-0520
- 电子ISSN1477-0539
- 文件大小895.11KB
- 发表时间2014
- DOI10.1039/c4ob00064a
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