Identification of N -(4-((1 R ,3 S ,5 S )-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

• 期刊名称Journal of Medicinal Chemistry
• 作者Burger, Matthew T.; Nishiguchi, Gisele; Han, Wooseok; Lan, Jiong; Simmons, Robert; Atallah, Gordana; Ding, Yu; Tamez, Victoriano; Zhang, Yanchen; Mathur, Michelle; Muller, Kristine; Bellamacina, Cornelia; Lindvall, Mika K.; Zang, Richard; Huh, Kay; Feucht, Paul; Zavorotinskaya, Tatiana; Dai, Yumin; Basham, Steve; Chan, Julie; Ginn, Elaine; Aycinena, Alex; Holash, Jocelyn; Castillo, Joseph; Langowski, John L.; Wang, Yingyun; Chen, Min Y.; Lambert, Amy; Fritsch, Christine; Kauffmann, Audry; Pfister, Estelle; Vanasse, K. Gary; Garcia, Pablo D.
• 印刷ISSN0022-2623
• 电子ISSN1520-4804
• 文件大小4098.19KB
• 发表时间2015-10-27
• DOI10.1021/acs.jmedchem.5b01275