Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of
<i>N</i>
-[(1
<i>R</i>
)-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)

Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N -[(1 R )-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)

Qiao, Jennifer X.; Wang, Tammy C.; Adam, Leonard P.; Chen, Alice Ye A.; Taylor, David S.; Yang, Richard Z.; Zhuang, Shaobin; Sleph, Paul G.; Li, Julia P.; Li, Danshi; Yin, Xiaohong; Chang, Ming; Chen, Xue-Qing; Shen, Hong; Li, Jianqing; Smith, Daniel; Wu, Dauh-Rurng; Leith, Leslie; Harikrishnan, Lalgudi S.; Kamau, Muthoni G.; Miller, Michael M.; Bilder, Donna; Rampulla, Richard; Li, Yi-Xin; Xu, Carrie; Lawrence, R. Michael; Poss, Michael A.; Levesque, Paul; Gordon, David A.; Huang, Christine S.; Finlay, Heather J.; Wexler, Ruth R.; Salvati, Mark E.

期刊名称Journal of Medicinal Chemistry
作者Qiao, Jennifer X.; Wang, Tammy C.; Adam, Leonard P.; Chen, Alice Ye A.; Taylor, David S.; Yang, Richard Z.; Zhuang, Shaobin; Sleph, Paul G.; Li, Julia P.; Li, Danshi; Yin, Xiaohong; Chang, Ming; Chen, Xue-Qing; Shen, Hong; Li, Jianqing; Smith, Daniel; Wu, Dauh-Rurng; Leith, Leslie; Harikrishnan, Lalgudi S.; Kamau, Muthoni G.; Miller, Michael M.; Bilder, Donna; Rampulla, Richard; Li, Yi-Xin; Xu, Carrie; Lawrence, R. Michael; Poss, Michael A.; Levesque, Paul; Gordon, David A.; Huang, Christine S.; Finlay, Heather J.; Wexler, Ruth R.; Salvati, Mark E.
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小1549.45KB
发表时间2015-11-17
DOI10.1021/acs.jmedchem.5b01363

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Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N -[(1 R )-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)