Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors

Cee, Victor J.; Chavez, Frank; Herberich, Bradley; Lanman, Brian A.; Pettus, Liping H.; Reed, Anthony B.; Wu, Bin; Wurz, Ryan P.; Andrews, Kristin L.; Chen, Jie; Hickman, Dean; Laszlo, Jimmy; Lee, Matthew R.; Guerrero, Nadia; Mattson, Bethany K.; Nguyen, Yen; Mohr, Christopher; Rex, Karen; Sastri, Christine E.; Wang, Paul; Wu, Qiong; Wu, Tian; Xu, Yang; Zhou, Yihong; Winston, Jeffrey T.; Lipford, J. Russell; Tasker, Andrew S.; Wang, Hui-Ling

期刊名称ACS Medicinal Chemistry Letters
作者Cee, Victor J.; Chavez, Frank; Herberich, Bradley; Lanman, Brian A.; Pettus, Liping H.; Reed, Anthony B.; Wu, Bin; Wurz, Ryan P.; Andrews, Kristin L.; Chen, Jie; Hickman, Dean; Laszlo, Jimmy; Lee, Matthew R.; Guerrero, Nadia; Mattson, Bethany K.; Nguyen, Yen; Mohr, Christopher; Rex, Karen; Sastri, Christine E.; Wang, Paul; Wu, Qiong; Wu, Tian; Xu, Yang; Zhou, Yihong; Winston, Jeffrey T.; Lipford, J. Russell; Tasker, Andrew S.; Wang, Hui-Ling
印刷ISSN1948-5875
电子ISSN1948-5875
文件大小1688.37KB
发表时间2016-02-12
DOI10.1021/acsmedchemlett.5b00403

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Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors