Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit

Gerstenberger, Brian S.; Trzupek, John D.; Tallant, Cynthia; Fedorov, Oleg; Filippakopoulos, Panagis; Brennan, Paul E.; Fedele, Vita; Martin, Sarah; Picaud, Sarah; Rogers, Catherine; Parikh, Mihir; Taylor, Alexandria; Samas, Brian; O’Mahony, Alison; Berg, Ellen; Pallares, Gabriel; Torrey, Adam D.; Treiber, Daniel K.; Samardjiev, Ivan J.; Nasipak, Brian T.; Padilla-Benavides, Teresita; Wu, Qiong; Imbalzano, Anthony N.; Nickerson, Jeffrey A.; Bunnage, Mark E.; Müller, Susanne; Knapp, Stefan; Owen, Dafydd R.

期刊名称Journal of Medicinal Chemistry
作者Gerstenberger, Brian S.; Trzupek, John D.; Tallant, Cynthia; Fedorov, Oleg; Filippakopoulos, Panagis; Brennan, Paul E.; Fedele, Vita; Martin, Sarah; Picaud, Sarah; Rogers, Catherine; Parikh, Mihir; Taylor, Alexandria; Samas, Brian; O’Mahony, Alison; Berg, Ellen; Pallares, Gabriel; Torrey, Adam D.; Treiber, Daniel K.; Samardjiev, Ivan J.; Nasipak, Brian T.; Padilla-Benavides, Teresita; Wu, Qiong; Imbalzano, Anthony N.; Nickerson, Jeffrey A.; Bunnage, Mark E.; Müller, Susanne; Knapp, Stefan; Owen, Dafydd R.
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小9459.05KB
发表时间2016-05-03
DOI10.1021/acs.jmedchem.6b00012

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Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit