Optimization of Tubulysin Antibody-Drug-Conjugates: A Case Study in Addressing ADC Metabolism.

Tumey, L. Nathan; Leverett, Carolyn A; Vetelino, Beth C.; Li, Fengping; Rago, Brian; Han, Xiaogang; Loganzo, Frank; Musto, Sylvia; Bai, Guoyun; Sukuru, Sai Chetan K; Graziani, Edmund Idris; Puthenveetil, Sujiet; Casavant, Jeffrey; Ratnayake, Anokha Sayani; Marquette, Kimberly; Hudson, Sarah; Doppalapudi, Venkata Ramana; Stock, Joseph R.; Tchistiakova, Lioudmila; Bessire, Andrew J.; Clark, Tracey; Lucas, Judy; Hosselet, Christine; O'Donnell, Christopher J.; Subramanyam, Chakrapani

期刊名称ACS Medicinal Chemistry Letters
作者Tumey, L. Nathan; Leverett, Carolyn A; Vetelino, Beth C.; Li, Fengping; Rago, Brian; Han, Xiaogang; Loganzo, Frank; Musto, Sylvia; Bai, Guoyun; Sukuru, Sai Chetan K; Graziani, Edmund Idris; Puthenveetil, Sujiet; Casavant, Jeffrey; Ratnayake, Anokha Sayani; Marquette, Kimberly; Hudson, Sarah; Doppalapudi, Venkata Ramana; Stock, Joseph R.; Tchistiakova, Lioudmila; Bessire, Andrew J.; Clark, Tracey; Lucas, Judy; Hosselet, Christine; O'Donnell, Christopher J.; Subramanyam, Chakrapani
印刷ISSN1948-5875
电子ISSN1948-5875
文件大小815.27KB
发表时间2016-06-22
DOI10.1021/acsmedchemlett.6b00195

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Optimization of Tubulysin Antibody-Drug-Conjugates: A Case Study in Addressing ADC Metabolism.