Discovery of Novel Spiro[3H-indole-3,2´-pyrrolidin]-2(1H)-one Compounds as Chemically Stable, and Orally Active Inhibitors of the MDM2–p53 Interaction

Gollner, Andreas; Rudolph, Dorothea; Arnhof, Heribert; Bauer, Markus; Blake, Sophia Maria; Boehmelt, Guido; Cockcroft, Xiao-Ling; Dahmann, Georg; Ettmayer, Peter; Gerstberger, Thomas; Karolyi-Oezguer, Jale; Kessler, Dirk; Kofink, Christiane; Ramharter, Juergen; Rinnenthal, Jörg; Savchenko, Alexander; Schnitzer, Renate; Weinstabl, Harald; Weyer-Czernilofsky, Ulrike; Wunberg, Tobias; McConnell, Darryl B.

期刊名称Journal of Medicinal Chemistry
作者Gollner, Andreas; Rudolph, Dorothea; Arnhof, Heribert; Bauer, Markus; Blake, Sophia Maria; Boehmelt, Guido; Cockcroft, Xiao-Ling; Dahmann, Georg; Ettmayer, Peter; Gerstberger, Thomas; Karolyi-Oezguer, Jale; Kessler, Dirk; Kofink, Christiane; Ramharter, Juergen; Rinnenthal, Jörg; Savchenko, Alexander; Schnitzer, Renate; Weinstabl, Harald; Weyer-Czernilofsky, Ulrike; Wunberg, Tobias; McConnell, Darryl B.
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小1705.46KB
发表时间2016-10-24
DOI10.1021/acs.jmedchem.6b00900

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Discovery of Novel Spiro[3H-indole-3,2´-pyrrolidin]-2(1H)-one Compounds as Chemically Stable, and Orally Active Inhibitors of the MDM2–p53 Interaction