Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology

Michno, Wojciech; Nyström, Sofie; Wehrli, Patrick; Lashley, Tammaryn; Brinkmalm, Gunnar; Guerard, Laurent; Syvänen, Stina; Sehlin, Dag; Kaya, Ibrahim; Brinet, Dimitri; Nilsson, K. Peter R.; Hammarström, Per; Blennow, Kaj; Zetterberg, Henrik; Hanrieder, Jörg

期刊名称Journal of Biological Chemistry
作者Michno, Wojciech; Nyström, Sofie; Wehrli, Patrick; Lashley, Tammaryn; Brinkmalm, Gunnar; Guerard, Laurent; Syvänen, Stina; Sehlin, Dag; Kaya, Ibrahim; Brinet, Dimitri; Nilsson, K. Peter R.; Hammarström, Per; Blennow, Kaj; Zetterberg, Henrik; Hanrieder, Jörg
印刷ISSN0021-9258
电子ISSN1083-351X
文件大小2953.16KB
发表时间2019-02-27
DOI10.1074/jbc.RA118.006604

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Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology